Estimate of the Association of IGF-I and IGFALS Genes with Growth Traits in Hamdani Sheep

IGF-I and IGFALS play a vital stimulator role in skeletal growth, cell differentiation, metabolism, other physiological processes. A total of 65 (male female) animals were used the study. Animals measured for growth traits at birth weight, weaning weights 6 months. The average daily gain (ADG) was calculated from to (ADG1) 6th month (ADG2). PCR-RFLP analysis detect polymorphism 5' regulatory region Exon 1. Three genotypes (AA, AB BB) observed IGF-I/BfoI locus with allele genotype frequency 0.79(A) 0.21(B); 0.71(AA), 0.15(AB) 0.14(BB). Also, three found IGFALS/HinfI site as 0.22(A) 0.78(B); 0.11(AA), 0.23(AB) 0.66(BB). genes agreement Hardy-Weinberg equilibrium (p>0.05). Association suggested that significantly affected (P<0.05). In terms AA higher than BB. had ADG2 compared genotypes. gene weight addition, BB ADG1 It is may be potential molecular marker Hamdani sheep.